{"id":2281,"date":"2025-11-01T14:29:38","date_gmt":"2025-11-01T14:29:38","guid":{"rendered":"https:\/\/usheritalia.it\/dr-giacomo-calzetti\/"},"modified":"2026-04-21T15:53:14","modified_gmt":"2026-04-21T15:53:14","slug":"dr-giacomo-calzetti","status":"publish","type":"post","link":"https:\/\/usheritalia.it\/es\/dr-giacomo-calzetti\/","title":{"rendered":"Dr Giacomo Calzetti"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>U:<\/strong> Gracias, Dr. Calzetti, por su disponibilidad para esta entrevista.<br>Sabemos que usted est\u00e1 trabajando en un estudio que tambi\u00e9n concierne a las personas con el S\u00edndrome de Usher.<br>\u00bfDe qu\u00e9 estudio se trata?<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>C:<\/strong> Se trata del estudio Uni-Rare, abreviaci\u00f3n de \u201cEstudio universal sobre genes raros: registro y estudio de historia natural de las distrofias retinianas asociadas a variantes gen\u00e9ticas que causan enfermedades raras\u201d. Como indica el nombre, es un estudio realizado a nivel mundial cuyo objeto son las enfermedades raras de la retina, entre ellas el S\u00edndrome de Usher.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>U:<\/strong> \u00bfDe qu\u00e9 formas del S\u00edndrome de Usher se ocupa el estudio Uni-Rare?<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>C:<\/strong> El estudio Uni-Rare abarca todas las formas del S\u00edndrome de Usher excepto la 2A. Por lo tanto, se ocupa de las formas del S\u00edndrome de Usher debidas a mutaciones en los siguientes genes:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>gen MYO7A, causa del s\u00edndrome de Usher 1B<\/li>\n\n\n\n<li>gen USH1C, causa del s\u00edndrome de Usher 1C<\/li>\n\n\n\n<li>gen CDH23, causa del s\u00edndrome de Usher 1D<\/li>\n\n\n\n<li>gen SANS, causa del s\u00edndrome de Usher 1G<\/li>\n\n\n\n<li>gen CIB2, causa del s\u00edndrome de Usher 1J<\/li>\n\n\n\n<li>gen ADGRV1, causa del s\u00edndrome de Usher 2C<\/li>\n\n\n\n<li>gen CLRN1, causa del s\u00edndrome de Usher 3A<\/li>\n\n\n\n<li>gen HARS1, causa del s\u00edndrome de Usher 3B<\/li>\n\n\n\n<li>gen ARSG, causa del s\u00edndrome de Usher 4<\/li>\n<\/ul>\n\n\n\n<div style=\"height:55px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">Se puede afirmar que Uni-Rare representa uno de los estudios m\u00e1s importantes actualmente en curso para estas formas del S\u00edndrome de Usher.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>U:<\/strong> \u00bfCu\u00e1les son los objetivos que persigue el estudio Uni-Rare?<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>C:<\/strong> Uni-Rare tiene dos objetivos principales:<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li>medir la evoluci\u00f3n de la degeneraci\u00f3n retiniana espec\u00edfica para cada gen, con el fin de evaluar correctamente la posible eficacia de nuevos tratamientos durante los ensayos que seguir\u00e1n a Uni-Rare;<\/li>\n\n\n\n<li>crear un registro de pacientes id\u00f3neos para participar en estos ensayos de nuevos tratamientos.<\/li>\n<\/ol>\n\n\n\n<div style=\"height:69px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>U:<\/strong> La Foundation Fighting Blindness financia el estudio.<br>\u00bfLa financiaci\u00f3n es suficiente para llevarlo a cabo?<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>C:<\/strong> S\u00ed, la Foundation Fighting Blindness pone a disposici\u00f3n un presupuesto para los investigadores de Uni-Rare. Este presupuesto ha sido suficiente para iniciar el estudio en Italia, en la cl\u00ednica Vista Vision de Brescia. Sin embargo, para llevar adelante el estudio necesitamos apoyo econ\u00f3mico, especialmente para ampliar el equipo de investigaci\u00f3n, que se ocupa de los diversos aspectos, tambi\u00e9n administrativo-burocr\u00e1ticos, de este proyecto cient\u00edfico tan exigente.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>U:<\/strong> Uno de los objetivos estatutarios de USHER Italia A.P.S. es apoyar y financiar la investigaci\u00f3n m\u00e9dico-cient\u00edfica para la cura del S\u00edndrome de Usher. Si usted lo desea, su estudio ser\u00e1 uno de los proyectos para los que pediremos a las personas sensibles y generosas que nos ayuden con donaciones, incluso peque\u00f1as, seg\u00fan las posibilidades de cada uno.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>C:<\/strong> Esto ayudar\u00eda enormemente al desarrollo del estudio. Cada contribuci\u00f3n, incluso la m\u00e1s peque\u00f1a, es un peque\u00f1o empuj\u00f3n hacia adelante para alcanzar nuestro objetivo: encontrar una cura para el S\u00edndrome de Usher.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>U:<\/strong> Gracias, Dr. Calzetti, por esta entrevista. \u00a1Hasta pronto!<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>C:<\/strong> \u00a1Gracias a USHER Italia A.P.S.!<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Investigatore Principale dello studio Uni-Rare, Clinica Vista Vision, Brescia (IT)<\/p>\n","protected":false},"author":2,"featured_media":2259,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[28],"tags":[],"class_list":["post-2281","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-intervista-es"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Dr Giacomo Calzetti - 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